TIGR Matrix

TIGR® matrix – Longterm Resorbable 100% Synthetic Mesh (non-animal)

TIGR Matrix Surgical Mesh is the world’s 1st long-term resorbable 100% synthetic matrix.  It is warp knitted from two different resorbable fibers that degrade at different rates following implantation.

TIGR Matrix was developed based on the hypothesis that soft tissue positively remodels in response to the stimulus of increased mechanical load. It is strong for 6-9 months and gone in 3 years.

TIGR degrade

The Ideal Matrix should be ………Strong when required, gone when not.

The ideal surgical synthetic matrix for use in Abdominal Wall Repair (AWR),  Sub-pectoral and Pre-pectoral Breast Reconstruction, secondary Breast augmentation, mastopexy support and sling procedure, should be ready to use (without long lasting washing process) mouldable, but still mechanically stable, should not cause allergic, immunologic or toxic reaction and should rapidly integrate into the tissue.  The cost of the matrix should also be a consideration, as hospitals and insurance providers will increasingly look for proof and cost effectiveness in the future.

Mode of Action

The first fibre is a copolymer of glycolide lactide and trimethylene carbonate. The second fibre is a copolymer of lactide and trimethylene carbonate. Both fibres degrade by bulk hydrolysis once implanted, unlike ADM’s which are enzymatically digested.  This has the benefit of being predicable in humans, whereas the breakdown of proteins associated with animal tissue is very dependent on the host.   This unique patented dual-fibre design provides an initial high strength / high stability configuration, with gradually increasing mechanical compliance over time – allowing for tissue expansion – as the device loses strength and is fully resorbed at 3 years.

After an initial 2 week healing phase the increasing mechanical compliance results in a gradual transition of load from the mesh to the patient. The macroporous structure (pore size 1-1.5mm) is designed to permit tissue integration for tissue repair.

TIGR clinica1TIGR clinical2

At 4 months post implantation, both fibres of the TIGR Matrix have integrated, leaving a collagen structure approx. 4-6mm deep, with no remaining mesh and ample new  reinforcement.

At 12 months post implantation -the fast degrading fibre has “gone” and the slow fibre is aiding tissue integration.

TIGR is an ideal mesh for prepectoral breast reconstruction after skin sparring mastectomy.  TIGR Mesh can be used to overlay a breast implant, even creating some “designed” ptosis by fixing the sutures under the bottom edge of the implant and over the entire device.  Over 12 months the TIGR Mesh is replaced by host tissue to create a soft, flexible layer of collagen over the implant.

It is also the perfect product to use as an onlay to prevent incisional hernia. Prophylactic Mesh Reinforcement (PMR) has been clinically proven to significantly reduce the risk of incisional hernia, especially in high risk patients. TIGR gives you the additional support across the internal wound to protect against herniation, it is slowly replaced with host tissue to give permanent strength and it leaves you none of the complications of a permanent mesh.

Available in 3 sizes;
  • TIGR Matrix 10 x 15 cm  NSTM1015E
  • TIGR Matrix 15 x 20 cm  NSTM1520E
  • TIGR Matrix 20 x 30 cm  NSTM2030E

For more information and to read the latest clinical publications please click here 

http://novusscientific.com/row/

Clinical Publications

Schenk TIGR matrix in breast reconstruction Jan 16 2015
Todd J 2015 Case CoBra Conference poster